Manganese dioxide (MnO2) nanozymes possess excellent enzyme-like oxidative activity (OXD activity). The template method is a classic means of defect regulation, which introduces oxygen vacancies (Ov) into MnO2 to further enhance its enzyme-like oxidative activity. However, the existing Ov generation templates have drawbacks such as high cost, poor biocompatibility, and incomplete template dissolution leading to residual toxicity, which greatly limit their application in the field of biocatalysis. Therefore, developing a green template with economic cost, good biocompatibility, and no toxicity after in vivo degradation for the preparation of high-performance MnO2 nanozymes is of great significance for their practical application.
Professor Zhang Yihhe and Professor Tong Wangxushe from the School of Materials Science and Engineering, China University of Geosciences (Beijing), guided graduate student Li Yao to prepare high-activity MnO2/ATP nanozymes using natural clay mineral attapulgite (ATP) as the oxygen vacancy (Ov) generation template, and further studied the generation mechanism of Ov and its regulatory mechanism on the enzyme-like oxidative activity of MnO2/ATP nanozymes. This work was titled "Attapulgite Template for Oxygen Vacancies Boost of Manganese Dioxide Nanozymes With High Oxidase-Like Activity" and was published in the journal Small.
Original link: https://onlinelibrary.wiley.com/doi/10.1002/smll.202512686