product information:

Name: Manganese Oxide Nanoenzyme: MnO2, Mn3O4 NZs

Product performance: Multi-enzyme activity: catalase-like, superoxide dismutase-like, glutathione peroxidase-like, with antioxidant function.

Application field: Its catalase-like activity can decompose H2O2 ultrasonic oxygen in the tumor microenvironment, thereby solving the hypoxia problem of photodynamic therapy, sonodynamic therapy, and radiotherapy; its glutathione peroxidase-like activity It can deplete the antioxidant glutathione GSH in the tumor microenvironment, thereby promoting the above-mentioned pro-oxidation treatment; after reacting with H2O2 and GSH, manganese oxide nanozyme degrades to Mn2+, which can promote the Fenton reaction and catalyze the production of hydroxyl radicals by H2O2 , To further promote oxidation treatment of tumors, and the Mn2+ produced at the same time has the function of magnetic resonance imaging; manganese oxide usually has strong near-infrared light absorption capacity and can be used for photothermal therapy and photoacoustic imaging; Mn3O4 has certain magnetic properties and can be used for magnetic resonance imaging ; Decompose H2O2 to produce oxygen bubbles, which can be used for ultrasound imaging; it can also be combined with chemotherapeutic drugs, gene drugs, etc. to achieve combined therapy